7-Ethyl-10-hydroxycamptothecin

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Catalog Number INT86639523
Alternative Name(s) 7-10-hydroxycamptothecin;(4S)-4,9-Dihydroxy-4,11-diethyl-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;(4S)-4,9-Dihydroxy-Chemicalbook4α,11-diethyl-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione;EHCPT;7-Ethyl-10-hydroxy-CPT(Camptothecine),SN-38
Research Area Intermediates
Molecular Formula C22H20N2O5
CAS# 86639-52-3
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7-Ethyl-10-hydroxycamptothecin

7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan [DB00762], a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer. SN 38 has been used in trials studying the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung Cancer, Metastatic Colorectal Cancer, and Triple Negative Breast Cancer, among others.

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Catalog Number PIPE-0747
Alternative Name(s) 7-Ethyl-10-hydroxycamptothecin SN 38 SN 38 lactone
Research Area Natural Extract
Molecular Formula C22H20N2O5
CAS# 86639-52-3
Purity 0.98%
SMILES CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)O
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