Tideglusib
Tideglusib is an irreversible, non ATP-competitive GSK-3β inhibitor with IC50 of 60 nM in a cell-free assay; fails to inhibit kinases with a Cys homologous to Cys-199 located in the active site. Phase 2.
| Trivial name | NP031112, NP-12 |
| Catalog Number | S2823 |
| Molecular Formula | C19H14N2O2S |
| CAS# | 865854-05-3 |
| Inchi | InChI=1S/C19H14N2O2S/c22-18-20(13-14-7-2-1-3-8-14)19(23)24-21(18)17-12-6-10-15-9-4-5-11-16(15)17/h1-12H,13H2 |
| Inchi Key | PMJIHLSCWIDGMD-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)CN2C(=O)N(SC2=O)C3=CC=CC4=CC=CC=C43 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/tideglusib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Tideglusib-chemical-structure-s2823.gif |