MK-28
MK-28 is a potent and selective activator of PERK. MK-28 exhibits an IC50 ~3-fold higher than CCT020312 in rescuing mutant huntingtin protein (mHtt)-expressing striatal neurons from apoptosis. MK-28 exhibits remarkable pharmacokinetic properties and high BBB penetration in mice.
Catalog Number | S6952 |
Molecular Formula | C24H20N4O2 |
CAS# | 864388-65-8 |
Inchi | #N/A |
Inchi Key | #N/A |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/mk-28.html |
Additional Information | https://file.selleck.cn/downloads/struct/S6952-MK-28-chemical-structure.png |