ML-180
ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist with an IC50 of 3.7 µM. ML-180 is inactive for steroidogenic factor-1 (SF-1; NR5A1; IC50>10 µM). ML-180 has the potential for LRH-1-dependent cancers .
| Trivial name | SR1848 |
| Catalog Number | CSN27223 |
| Alternative Name(s) | SR1848 |
| Research Area | Cancer |
| Molecular Formula | C20H25ClN4O2 |
| CAS# | 863588-32-3 |
| Purity | ≥98% |
| SMILES | O=C1N(C2CCCCC2)C(C=C(N3CCN(C4=CC=CC(Cl)=C4)CC3)N1)=O |
| Size | 10mg |
| Supplier Page | https://www.csnpharm.com/products/ml-180.html |