Ralimetinib (LY2228820) dimesylate
Ralimetinib (LY2228820) dimesylate is a novel and potent inhibitor of p38 MAPK with IC50 of 7 nM in a cell-free assay, does not alter p38 MAPK activation. Phase 1/2.
Trivial name | N/A |
Catalog Number | S1494 |
Molecular Formula | C24H29FN6.2CH4O3S |
CAS# | 862507-23-1 |
Inchi | InChI=1S/C24H29FN6.2CH4O3S/c1-23(2,3)13-31-20-17(28-22(31)26)12-11-16(27-20)19-18(14-7-9-15(25)10-8-14)29-21(30-19)24(4,5)6;2*1-5(2,3)4/h7-12H,13H2,1-6H3,(H2,26,28)(H,29,30);2*1H3,(H,2,3,4) |
Inchi Key | NARMJPIBAXVUIE-UHFFFAOYSA-N |
SMILES | CC(C)(C)CN1C2=C(C=CC(=N2)C3=C(N=C(N3)C(C)(C)C)C4=CC=C(C=C4)F)N=C1N.CS(=O)(=O)O.CS(=O)(=O)O |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/LY2228820.html |
Additional Information | https://file.selleck.cn/downloads/struct/LY2228820-chemical-structure-S1494.gif |