Motesanib Diphosphate (AMG-706)

Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit (c-Kit), ~10-fold more selective for VEGFR than PDGFR and Ret. Phase 3.

Trivial name N/A
Catalog Number S1032
Molecular Formula C29H50O2
CAS# 857876-30-3
Inchi InChI=1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3
Inchi Key GVJHHUAWPYXKBD-UHFFFAOYSA-N
SMILES CC1=C(C2=C(CCC(O2)(C)CCCC(C)CCCC(C)CCCC(C)C)C(=C1O)C)C
Size 50mg
Supplier Page http://www.selleckchem.com/products/Motesanib-Diphosphate.html
Additional Information https://file.selleck.cn/downloads/struct/Motesanib-AMG-706-chemical-structure-S1032.gif