Motesanib Diphosphate (AMG-706)

Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit (c-Kit), ~10-fold more selective for VEGFR than PDGFR and Ret. Phase 3.

Price Not Available 10mg Motesanib Diphosphate (AMG-706) Supplier Page

Trivial name	N/A
Catalog Number	S1032
Molecular Formula	C22H23N5O.2H3PO4
CAS#	857876-30-3
Inchi	InChI=1S/C22H23N5O.2H3O4P/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15;21-5(2,3)4/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28);2(H3,1,2,3,4)
Inchi Key	ONDPWWDPQDCQNJ-UHFFFAOYSA-N
SMILES	CC1(CNC2=C1C=CC(=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4)C.OP(=O)(O)O.OP(=O)(O)O
Size	10mg
Supplier Page	http://www.selleckchem.com/products/Motesanib-Diphosphate.html
Additional Information	https://file.selleck.cn/downloads/struct/Motesanib-AMG-706-chemical-structure-S1032.gif