WP1066
WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3. WP1066 has been used in trials studying the treatment of Melanoma, Brain Cancer, Solid Tumors, and Central Nervous System Neoplasms.
| Catalog Number | T2156 |
| Research Area | Chromatin/Epigenetic|||Stem Cells|||JAK/STAT signaling|||Angiogenesis|||Apoptosis |
| Molecular Formula | C17H14BrN3O |
| CAS# | 857064-38-1 |
| Purity | 99.07% |
| SMILES | C[C@@H](c1ccccc1)NC(=O)/C(=C/c1nc(ccc1)Br)/C#N |
| Size | 10 mg |
| Supplier Page | https://www.targetmol.com/compound/WP1066 |
| Additional Information | https://www.targetmol.com/datasheet/T2156 |
