WP1066
WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2 not JAK1 and JAK3. WP1066 induces apoptosis. Phase 1.
| Trivial name | N/A |
| Catalog Number | S2796 |
| Molecular Formula | C17H14BrN3O |
| CAS# | 857064-38-1 |
| Inchi | InChI=1S/C17H14BrN3O/c1-12(13-6-3-2-4-7-13)20-17(22)14(11-19)10-15-8-5-9-16(18)21-15/h2-10,12H,1H3,(H,20,22)/b14-10+/t12-/m0/s1 |
| Inchi Key | VFUAJMPDXIRPKO-LQELWAHVSA-N |
| SMILES | CC(C1=CC=CC=C1)NC(=O)C(=CC2=NC(=CC=C2)Br)C#N |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/wp1066.html |
| Additional Information | https://file.selleck.cn/downloads/struct/WP1066-chemical-structure-s2796.gif |