WP1066
WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2 not JAK1 and JAK3. WP1066 induces apoptosis. Phase 1.
| Trivial name | N/A |
| Catalog Number | S2796 |
| Molecular Formula | C15H22N2. 2HCl |
| CAS# | 857064-38-1 |
| Inchi | InChI=1S/C15H22N2.2ClH/c16-12-6-8-13(9-7-12)17-15-10-14(15)11-4-2-1-3-5-11;;/h1-5,12-15,17H,6-10,16H2;2*1H/t12?,13?,14-,15+;;/m0../s1 |
| Inchi Key | UCINOBZMLCREGM-RNNUGBGQSA-N |
| SMILES | C1CC(CCC1N)NC2CC2C3=CC=CC=C3.Cl.Cl |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/wp1066.html |
| Additional Information | https://file.selleck.cn/downloads/struct/WP1066-chemical-structure-s2796.gif |