(R)-(-)-Rolipram
(R)-(-)-Rolipram is the R-enantiomer of Rolipram. Rolipram is a selective inhibitor of phosphodiesterases PDE4 with IC50 of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.
| Trivial name | (R)-Rolipram, (-)-Rolipram |
| Catalog Number | E7689 |
| Molecular Formula | C23H36N6O5S |
| CAS# | 85416-75-7 |
| Inchi | InChI=1S/C23H36N6O5S/c1-14-8-10-29(18(12-14)22(31)32)21(30)17(6-4-9-26-23(24)25)28-35(33,34)19-7-3-5-16-11-15(2)13-27-20(16)19/h3,5,7,14-15,17-18,27-28H,4,6,8-13H2,1-2H3,(H,31,32)(H4,24,25,26)/t14-,15 ?,17+,18-/m1/s1 |
| Inchi Key | KXNPVXPOPUZYGB-IOVMHBDKSA-N |
| SMILES | CC1CCN(C(C1)C(=O)O)C(=O)C(CCCN=C(N)N)NS(=O)(=O)C2=CC=CC3=C2NCC(C3)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/r-rolipram.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7689-r-rolipram-chemical-structure-tube.png |