Dasatinib hydrochloride
Dasatinib hydrochloride (BMS-354825) is the hydrochloride salt form of dasatinib, an inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively.
| Trivial name | BMS-354825 HCl |
| Catalog Number | S5254 |
| Molecular Formula | C22H27Cl2N7O2S |
| CAS# | 854001-07-3 |
| Inchi | InChI=1S/C22H26ClN7O2S.ClH/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31;/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27);1H |
| Inchi Key | MSCGWICDJYLQOJ-UHFFFAOYSA-N |
| SMILES | CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO.Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/dasatinib-hydrochloride.html |
| Additional Information | https://file.selleck.cn/downloads/struct/dasatinib-hydrochloride-chemical-structure-s5254.gif |