K03861 (AUZ454)
K03861 (AUZ454) is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.
| Catalog Number | S8100 |
| Molecular Formula | C24H26F3N7O2 |
| CAS# | 853299-07-7 |
| Inchi | InChI=1S/C24H26F3N7O2/c1-33-10-12-34(13-11-33)15-16-2-3-18(14-20(16)24(25,26)27)31-23(35)30-17-4-6-19(7-5-17)36-21-8-9-29-22(28)32-21/h2-9,14H,10-13,15H2,1H3,(H2,28,29,32)(H2,30,31,35) |
| Inchi Key | PWDLXPJQFNVTNL-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)NC3=CC=C(C=C3)OC4=NC(=NC=C4)N)C(F)(F)F |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/k03861.html |
| Additional Information | https://file.selleck.cn/downloads/struct/k03861-chemical-structure-s8100.gif |