Galeterone
Galeterone (TOK-001) is a selective CYP17 inhibitor and androgen receptor (AR) antagonist with IC50 of 300 nM and 384 nM, respectively, and is a potent inhibitor of human prostate tumor growth. Phase 2.
| Trivial name | TOK-001 |
| Catalog Number | S2803 |
| Molecular Formula | C26H32N2O |
| CAS# | 851983-85-2 |
| Inchi | InChI=1S/C26H32N2O/c1-25-13-11-18(29)15-17(25)7-8-19-20-9-10-24(26(20,2)14-12-21(19)25)28-16-27-22-5-3-4-6-23(22)28/h3-7,10,16,18-21,29H,8-9,11-15H2,1-2H3/t18-,19?,20?,21?,25-,26-/m0/s1 |
| Inchi Key | PAFKTGFSEFKSQG-BLYLLKCRSA-N |
| SMILES | CC12CCC(CC1=CCC3C2CCC4(C3CC=C4N5C=NC6=CC=CC=C65)C)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/galeterone-tok-001.html |
| Additional Information | https://file.selleck.cn/downloads/struct/VN124-1-chemical-structure-s2803.gif |