Zatebradine

Zatebradine is a potent HCN channels antagonist. It could decrease the heartbeat in a reversible manner. Its IC50 value is 10 uM of 92% inhibition of the hHCN1. It reduced the activity of oriens-lacunosum moleculare interneurons in wild-type and decreased the frequency of spontaneous inhibitory currents in postsynaptic CA1 pyramidal cells. It is a specific bradycardic agent.

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Catalog Number	85175-67-3
Alternative Name(s)	2H-3-Benzazepin-2-one,3-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-;Zatebradinum;Zatebradina;3-[3-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one;UL-FS49
Molecular Formula	C26H36N2O5
CAS#	85175-67-3
Purity	>98%
Inchi	InChI=1S/C26H36N2O5/c1-27(13-9-19-7-8-22(30-2)23(15-19)31-3)11-6-12-28-14-10-20-16-24(32-4)25(33-5)17-21(20)18-26(28)29/h7-8,15-17H,6,9-14,18H2,1-5H3
Inchi Key	KEDQCFRVSHYKLR-UHFFFAOYSA-N
Size	Please inquire
Supplier Page	https://www.bocsci.com/zatebradine-cas-85175-67-3-item-138915.html