Danoprevir
Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. Phase 2.
| Trivial name | ITMN-191, RG7227 |
| Catalog Number | S1183 |
| Molecular Formula | C35H46FN5O9S |
| CAS# | 850876-88-9 |
| Inchi | InChI=1S/C35H46FN5O9S/c1-34(2,3)50-32(45)37-27-13-8-6-4-5-7-11-22-17-35(22,31(44)39-51(47,48)24-14-15-24)38-29(42)28-16-23(19-41(28)30(27)43)49-33(46)40-18-21-10-9-12-26(36)25(21)20-40/h7,9-12,22-24,2 7-28H,4-6,8,13-20H2,1-3H3,(H,37,45)(H,38,42)(H,39,44)/b11-7-/t22-,23-,27+,28+,35-/m1/s1 |
| Inchi Key | ZVTDLPBHTSMEJZ-JSZLBQEHSA-N |
| SMILES | CC(C)(C)OC(=O)NC1CCCCCC=CC2CC2(NC(=O)C3CC(CN3C1=O)OC(=O)N4CC5=C(C4)C(=CC=C5)F)C(=O)NS(=O)(=O)C6CC6 |
| Size | 2mg |
| Supplier Page | http://www.selleckchem.com/products/Danoprevir.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Danoprevir-chemical-structure-s1183.jpg |