Alvelestat (AZD9668)

Alvelestat (AZD9668, Avelestat) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases.
Phase 2.

Price Not Available 100mg Alvelestat (AZD9668) Supplier Page

Trivial name	Avelestat
Catalog Number	S7218
Molecular Formula	C25H22F3N5O4S
CAS#	848141-11-7
Inchi	InChI=1S/C24H20F3N5O4S/c1-31-21(8-9-30-31)15-10-20(22(33)29-12-17-6-7-19(13-28-17)37(2,35)36)23(34)32(14-15)18-5-3-4-16(11-18)24(25,26)27/h3-11,13-14H,12H2,1-2H3,(H,29,33)
Inchi Key	BSIRHPGCYXLICK-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)C(=O)NCC3=NC=C(C=C3)S(=O)(=O)C)C4=CC=NN4C
Size	100mg
Supplier Page	http://www.selleckchem.com/products/avelestat-azd9668.html
Additional Information	https://file.selleck.cn/downloads/struct/AZD9668-chemical-structure-s7218.gif