RO4929097
RO4929097 (RG-4733) is a γ secretase inhibitor with IC50 of 4 nM in a cell-free assay, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively. Phase 2.
Trivial name | RG-4733 |
Catalog Number | S1575 |
Molecular Formula | C55H96N14O13 |
CAS# | 847925-91-1 |
SMILES | CCC(C)C(NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(N)CCCCN)C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCCCN)C(O)=O |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/RO4929097.html |
Additional Information | https://file.selleck.cn/downloads/struct/RO4929097-chemical-structure-S1575.gif |