RO4929097
RO4929097 (RG-4733) is a γ secretase inhibitor with IC50 of 4 nM in a cell-free assay, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively. Phase 2.
Trivial name | RG-4733 |
Catalog Number | S1575 |
Molecular Formula | C54H69N11O10S2 |
CAS# | 847925-91-1 |
SMILES | CC(C)C1NC(=O)C(CCCCN)NC(=O)C(CC2=C[NH]C3=C2C=CC=C3)NC(=O)C(CC4=CC=C(O)C=C4)NC(=O)C(CSSCC(NC1=O)C(=O)NC(C(C)O)C(N)=O)NC(=O)C(N)CC5=CC6=CC=CC=C6C=C5 |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/RO4929097.html |
Additional Information | https://file.selleck.cn/downloads/struct/RO4929097-chemical-structure-S1575.gif |