RO4929097
RO4929097 (RG-4733) is a γ secretase inhibitor with IC50 of 4 nM in a cell-free assay, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively. Phase 2.
| Trivial name | RG-4733 | 
| Catalog Number | S1575 | 
| Molecular Formula | C54H69N11O10S2 | 
| CAS# | 847925-91-1 | 
| SMILES | CC(C)C1NC(=O)C(CCCCN)NC(=O)C(CC2=C[NH]C3=C2C=CC=C3)NC(=O)C(CC4=CC=C(O)C=C4)NC(=O)C(CSSCC(NC1=O)C(=O)NC(C(C)O)C(N)=O)NC(=O)C(N)CC5=CC6=CC=CC=C6C=C5 | 
| Size | 10mM/1mL | 
| Supplier Page | http://www.selleckchem.com/products/RO4929097.html | 
| Additional Information | https://file.selleck.cn/downloads/struct/RO4929097-chemical-structure-S1575.gif | 
                    