Delanzomib
Delanzomib is an orally active inhibitor of the chymotrypsin-like activity of proteasome with IC50 of 3.8 nM, with only marginal inhibition of the tryptic and peptidylglutamyl activities of the proteosome. Phase 1/2.
| Trivial name | CEP-18770 |
| Catalog Number | S1157 |
| Molecular Formula | C21H28BN3O5 |
| CAS# | 847499-27-8 |
| Inchi | InChI=1S/C21H28BN3O5/c1-13(2)16(22(29)30)12-23-21(28)19(14(3)26)25-20(27)18-11-7-10-17(24-18)15-8-5-4-6-9-15/h4-11,13-14,16,19,26,29-30H,12H2,1-3H3,(H,23,28)(H,25,27)/t14-,16+,19+/m1/s1 |
| Inchi Key | PPAJFLNVGDSLAB-ALKREAHSSA-N |
| SMILES | B(C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C1=CC=CC(=N1)C2=CC=CC=C2)(O)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/cep-18770.html |
| Additional Information | https://file.selleck.cn/downloads/struct/CEP-18770-chemical-structure-s1157.gif |