Rocaglamide
Rocaglamide (Roc-A), isolated from Aglaia species, is a potent inhibitor of heat shock factor 1 (HSF1) activation with IC50 of ~50 nM for HSF1. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also inhibits NF-κB activity. Rocaglamide exhibits anti-tumor activity.
| Trivial name | Roc-A |
| Catalog Number | S7428 |
| Molecular Formula | C29H31NO7 |
| CAS# | 84573-16-0 |
| SMILES | CN(C)C(=O)C1C(C2(C(C1O)(C3=C(O2)C=C(C=C3OC)OC)O)C4=CC=C(C=C4)OC)C5=CC=CC=C5 |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/rocaglamide.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s7428-rocaglamide-chemical-structure.gif |