Bitopertin
Bitopertin (RG1678,RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells.
| Trivial name | RG1678, RO-4917838 |
| Catalog Number | S8219 |
| Molecular Formula | C21H20F7N3O4S |
| CAS# | 845614-11-1 |
| Inchi | InChI=1S/C21H20F7N3O4S/c1-12(20(23,24)25)35-17-4-3-14(36(2,33)34)10-15(17)19(32)31-7-5-30(6-8-31)18-16(22)9-13(11-29-18)21(26,27)28/h3-4,9-12H,5-8H2,1-2H3/t12-/m0/s1 |
| Inchi Key | YUUGYIUSCYNSQR-LBPRGKRZSA-N |
| SMILES | CC(C(F)(F)F)OC1=C(C=C(C=C1)S(=O)(=O)C)C(=O)N2CCN(CC2)C3=C(C=C(C=N3)C(F)(F)F)F |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/bitopertin-rg1678-ro-4917838.html |
| Additional Information | https://file.selleck.cn/downloads/struct/bitopertin-rg1678-ro-4917838-chemical-structure-s8219.gif |