Varlitinib
Varlitinib (ARRY334543) is a selective and potent ErbB1(EGFR) and ErbB2(HER2) inhibitor with IC50 of 7 nM and 2 nM, respectively. Phase 2.
| Trivial name | ARRY334543 |
| Catalog Number | S2755 |
| Molecular Formula | C22H19ClN6O2S |
| CAS# | 845272-21-1 |
| Inchi | InChI=1S/C22H19ClN6O2S/c1-13-10-31-22(27-13)29-14-2-4-18-16(8-14)21(26-12-25-18)28-15-3-5-19(17(23)9-15)30-11-20-24-6-7-32-20/h2-9,12-13H,10-11H2,1H3,(H,27,29)(H,25,26,28)/t13-/m1/s1 |
| Inchi Key | UWXSAYUXVSFDBQ-CYBMUJFWSA-N |
| SMILES | CC1COC(=N1)NC2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=NC=CS5)Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/arry334543.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ARRY-334543-chemical-structure-s2755.gif |