AT7519
AT7519 is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM. It is less potent to CDK3 and little active to CDK7. AT7519 also decrease GSK3β phosphorylation. AT7519 induces apoptosis. Phase 2.
Trivial name | AT7519M |
Catalog Number | S1524 |
Molecular Formula | C17H19ClN2S |
CAS# | 844442-38-2 |
SMILES | CC1=CC2=C(C=C1)[N+](=C(S2)C3=CC=C(C=C3)N(C)C)C.[Cl-] |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/AT7519.html |
Additional Information | https://file.selleck.cn/downloads/struct/AT7519-chemical-structure-S1524.gif |