Mifepristone
Mifepristone is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.Mifepristone (RU486) can be used to induce animal models of Spontaneous Abortion.
| Trivial name | C-1073, RU 38486 |
| Catalog Number | S2606 |
| Molecular Formula | C15H15BrN4S |
| CAS# | 84371-65-3 |
| Inchi | InChI=1S/C15H14N4S.BrH/c16-9-11-5-7-12(8-6-11)14-10-20-15(17-14)19-18-13-3-1-2-4-13;/h5-8,10H,1-4H2,(H,17,19);1H |
| Inchi Key | XNWBCMSPDCSWSD-UHFFFAOYSA-N |
| SMILES | C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)C#N)C1.Br |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Mifepristone(Mifeprex).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Mifepristone-chemical-structure-s2606.gif |