Mifepristone
Mifepristone is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.Mifepristone (RU486) can be used to induce animal models of Spontaneous Abortion.
| Trivial name | C-1073, RU 38486 |
| Catalog Number | S2606 |
| Molecular Formula | C23H18N4O3 |
| CAS# | 84371-65-3 |
| Inchi | InChI=1S/C23H18N4O3/c24-22(28)14-4-6-15(7-5-14)23-26-20(21(27-23)17-3-1-2-10-25-17)16-8-9-18-19(13-16)30-12-11-29-18/h1-10,13H,11-12H2,(H2,24,28)(H,26,27) |
| Inchi Key | DPDZHVCKYBCJHW-UHFFFAOYSA-N |
| SMILES | C1COC2=C(O1)C=CC(=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Mifepristone(Mifeprex).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Mifepristone-chemical-structure-s2606.gif |