Mifepristone
Mifepristone is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.
| Trivial name | RU486, C-1073, RU 38486, RU-486 |
| Catalog Number | S2606 |
| Molecular Formula | C29H35NO2 |
| CAS# | 84371-65-3 |
| Inchi | InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1 |
| Inchi Key | VKHAHZOOUSRJNA-GCNJZUOMSA-N |
| SMILES | CC#CC1(CCC2C1(CC(C3=C4CCC(=O)C=C4CCC23)C5=CC=C(C=C5)N(C)C)C)O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Mifepristone(Mifeprex).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Mifepristone-chemical-structure-s2606.gif |