Canagliflozin (JNJ 28431754)
Canagliflozin (TA 7284, JNJ 28431754) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM in a cell-free assay, exhibits 413-fold selectivity over hSGLT1.
Trivial name | TA 7284 |
Catalog Number | S2760 |
Molecular Formula | C24H25FO5S |
CAS# | 842133-18-0 |
Inchi | InChI=1S/C24H25FO5S/c1-13-2-3-15(24-23(29)22(28)21(27)19(12-26)30-24)10-16(13)11-18-8-9-20(31-18)14-4-6-17(25)7-5-14/h2-10,19,21-24,26-29H,11-12H2,1H3/t19-,21-,22+,23-,24+/m1/s1 |
Inchi Key | XTNGUQKDFGDXSJ-ZXGKGEBGSA-N |
SMILES | CC1=C(C=C(C=C1)C2C(C(C(C(O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/canagliflozin.html |
Additional Information | https://file.selleck.cn/downloads/struct/Canagliflozin-chemical-structure-s2760.gif |