Canagliflozin (JNJ 28431754)
Canagliflozin (TA 7284, JNJ 28431754) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM in a cell-free assay, exhibits 413-fold selectivity over hSGLT1.
Trivial name | TA 7284 |
Catalog Number | S2760 |
Molecular Formula | C15H11NO3S2 |
CAS# | 842133-18-0 |
Inchi | InChI=1S/C15H11NO3S2/c17-14-8-7-11-4-1-2-5-12(11)13(14)10-16-21(18,19)15-6-3-9-20-15/h1-10,17H/b16-10+ |
Inchi Key | TVIVJHZHPKNDAQ-MHWRWJLKSA-N |
SMILES | C1=CC=C2C(=C1)C=CC(=C2C=NS(=O)(=O)C3=CC=CS3)O |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/canagliflozin.html |
Additional Information | https://file.selleck.cn/downloads/struct/Canagliflozin-chemical-structure-s2760.gif |