Pluripotin (SC1)
Pluripotin (SC1) is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. Maintains embryonic stem cell (ESC) self-renewal. Pluripotin also inhibits RSK1, RSK2, RSK3 and RSK4 with IC50 of 0.5 µM, 2.5 µM, 3.3 µM and 10.0 µM, respectively.
| Trivial name | N/A |
| Catalog Number | S7752 |
| Molecular Formula | C27H25F3N8O2 |
| CAS# | 839707-37-8 |
| Inchi | InChI=1S/C27H25F3N8O2/c1-15-8-9-20(32-24(39)17-6-5-7-19(11-17)27(28,29)30)12-21(15)38-14-18-13-31-25(34-23(18)36(3)26(38)40)33-22-10-16(2)35-37(22)4/h5-13H,14H2,1-4H3,(H,32,39)(H,31,33,34) |
| Inchi Key | NBZFRTJWEIHFPF-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)N3CC4=CN=C(N=C4N(C3=O)C)NC5=CC(=NN5C)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/pluripotin-sc1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/pluripotin-sc1-chemical-structure-s7752.gif |