Pluripotin
Pluripotin (SC1) regulates mouse embryonic stem cell (ESC) self-renewal. It was shown that SC1 is sufficient for sustaining long-term self-renewal of mouse ES cells in an undifferentiated state in the absence of LIF, feeder cells, or serum. SC1 acts through dual inhibition of Ras-GAP and ERK1 with Kd values of 98 and 212 nM, respectively.
| Catalog Number | ABS-049 |
| Alternative Name(s) | N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo- 1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)- 3-(trifluoromethyl)benzamide; SC1 |
| CAS# | 839707-37-8 |
| Inchi | InChI=1S/C27H25F3N8O2/c1-15-8-9-20(32-24(39)17-6-5-7-19(11-17)27(28,29)30)12-21(15)38-14-18-13-31-25(34-23(18)36(3)26(38)40)33-22-10-16(2)35-37(22)4/h5-13H,14H2,1-4H3,(H,32,39)(H,31,33,34) |
| Inchi Key | NBZFRTJWEIHFPF-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)N3CC4=CN=C(N=C4N(C3=O)C)NC5=CC(=NN5C)C |
| Size | Inquiry |
| Supplier Page | https://www.agingclocks.com/pluripotin-item-1513.html |