Domperidone monomaleate

Domperidone monomaleate (R33812 monomaleate) is a potent antagonist of dopamine D2 receptor that acts as an antiemetic and prokinetic agent by targeting the chemoreceptor trigger zone and motor function of the stomach and small intestine. It also inhibits cardiac Na⁺ channels such as Nav1.5, suggesting a potential molecular mechanism for cardiovascular side effects like malignant arrhythmias.

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Trivial name	R33812 monomaleate
Catalog Number	E6049
Molecular Formula	C29H32N4O3S
CAS#	83898-65-1
Inchi	InChI=1S/C29H32N4O3S/c1-2-37(35,36)32-24-15-16-26-25(19-24)27(29(34)31-26)28(22-9-5-3-6-10-22)30-23-13-11-21(12-14-23)20-33-17-7-4-8-18-33/h3,5-6,9-16,19,30,32H,2,4,7-8,17-18,20H2,1H3,(H,31,34)/b28-27 -
Inchi Key	GLDSKRNGVVYJAB-DQSJHHFOSA-N
SMILES	CCS(=O)(=O)NC1=CC2=C(C=C1)NC(=C2C(=NC3=CC=C(C=C3)CN4CCCCC4)C5=CC=CC=C5)O
Size	100mg
Supplier Page	http://www.selleckchem.com/products/domperidone-monomaleate.html
Additional Information	https://file.selleck.cn/downloads/struct/E6049-Domperidone-monomaleate-chemical-structure.png