AS1842856
AS1842856 is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 with IC50 of 33 nM. It could directly bind to the active Foxo1, but not the Ser256-phosphorylated form. AS1842856 suppresses autophagy.
| Trivial name | N/A |
| Catalog Number | S8222 |
| Molecular Formula | C18H22FN3O3 |
| CAS# | 836620-48-5 |
| Inchi | InChI=1S/C18H22FN3O3/c1-2-22-9-11(18(24)25)17(23)14-13(22)8-12(15(19)16(14)20)21-10-6-4-3-5-7-10/h8-10,21H,2-7,20H2,1H3,(H,24,25) |
| Inchi Key | MOMCHYGXXYBDCD-UHFFFAOYSA-N |
| SMILES | CCN1C=C(C(=O)C2=C1C=C(C(=C2N)F)NC3CCCCC3)C(=O)O |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/as1842856.html |
| Additional Information | https://file.selleck.cn/downloads/struct/as1842856-chemical-structure-s8222.gif |