Elagolix Sodium

Elagolix is a selective gonadotropin-releasing hormone receptor (GnRHR) antagonist with KD of 54 pM. It is in phase III clinical trials for the treatment of endometriosis and uterine leiomyoma. Elagolix was also under investigation for the treatment of prostate cancer and benign prostatic hyperplasia, but development for these indications was ultimately not pursued.

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Catalog Number API832720362
Alternative Name(s) Elagolix sodium salt Orlissa Elagolix sodium [USAN]
Research Area APIs for Endometriosis
Molecular Formula C32H29F5N3NaO5
CAS# 832720-36-2
SMILES CC1=C(C(=O)N(C(=O)N1CC2=C(C=CC=C2F)C(F)(F)F)CC(C3=CC=CC=C3)NCCCC(=O)[O-])C4=C(C(=CC=C4)OC)F.[Na+]
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