Methylprednisolone
Methylprednisolone is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.
Trivial name | NSC-19987, U 7532 |
Catalog Number | S1733 |
Molecular Formula | C28H40BrN7O4 |
CAS# | 83-43-2 |
Inchi | InChI=1S/C28H40BrN7O4/c1-16(2)35(12-6-11-31-27(39)34-18-9-7-17(8-10-18)28(3,4)5)14-20-22(37)23(38)26(40-20)36-13-19(29)21-24(30)32-15-33-25(21)36/h7-10,13,15-16,20,22-23,26,37-38H,6,11-12,14H2,1-5H3,( H2,30,32,33)(H2,31,34,39)/t20-,22-,23-,26-/m1/s1 |
Inchi Key | IQCKJUKAQJINMK-HUBRGWSESA-N |
SMILES | CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)CC2C(C(C(O2)N3C=C(C4=C(N=CN=C43)N)Br)O)O |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/Methylprednisolone.html |
Additional Information | https://file.selleck.cn/downloads/struct/Methylprednisolone-chemical-structure-S1733.gif |