C188

C188 is a cell-permeable naphthol compound and a STAT3 inhibitor. C188 inhibits IL-6-stimulated STAT3 Tyr705 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket, while exhibiting little effect against IFN-γ-stimulated HepG2 cellular STAT1 phosphorylation.

Price Not Available 10 mg C188 Supplier Page

Catalog Number	T26936
Alternative Name(s)	C-188 , C 188 , Cpd188 , STAT3-IN-C188 , Cpd-188
Molecular Formula	C19H15NO7S2
CAS#	823828-18-8
SMILES	O=C(O)C1=CC=C(C=C1)S(=O)(=O)NC2=CC(SCC(=O)O)=C(O)C=3C=CC=CC23
Size	10 mg
Supplier Page	https://www.targetmol.com/compound/C188
Additional Information	https://www.targetmol.com/datasheet/T26936