Rottlerin
Rottlerin (Mallotoxin, NSC 56346, NSC 94525), a natural compound purified from Mallotus Philippinensis, is a specific Protein kinase inhibitor with IC50 of 3 μM, 6 μM and 5.3 μM for PKCδ(from baculovirus-infected Sf9 insect cells), PKCδ(from porcine spleen) and CaM kinase III, respectively. Rottlerin also inhibits PKCα, PKCγ, PKCβ, PKCη, CKII and PKA with IC50 of 30 μM, 40 μM, 42 μM, 82 μM, 30 μM and 78 μM, respectively.
Trivial name | Mallotoxin, NSC 56346, NSC 94525 |
Catalog Number | S7862 |
Molecular Formula | C30H28O8 |
CAS# | 82-08-6 |
SMILES | CC1=C(C(=C(C(=C1O)C(=O)C)O)CC2=C(C(=C3C(=C2O)C=CC(O3)(C)C)C(=O)C=CC4=CC=CC=C4)O)O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/rottlerin.html |
Additional Information | https://file.selleck.cn/downloads/struct/s7862-rottlerin-chemical-structure.gif |