Apatinib (YN968D1) mesylate
Apatinib mesylate (YN968D1, Rivoceranib) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib mesylate induces both autophagy and apoptosis.
| Trivial name | YN968D1, Rivoceranib |
| Catalog Number | S2221 |
| Molecular Formula | C27H28N2O3 |
| CAS# | 1218779-75-9 |
| Inchi | InChI=1S/C27H28N2O3/c30-26(28-24-15-17-29(18-16-24)19-21-7-3-1-4-8-21)20-32-25-13-11-23(12-14-25)27(31)22-9-5-2-6-10-22/h1-14,24H,15-20H2,(H,28,30) |
| Inchi Key | SHHUPGSHGSNPDB-UHFFFAOYSA-N |
| SMILES | C1CN(CCC1NC(=O)COC2=CC=C(C=C2)C(=O)C3=CC=CC=C3)CC4=CC=CC=C4 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Apatinib-YN968D1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Apatinib-YN968D1-chemical-structure-S2221.gif |