Apatinib (YN968D1) mesylate
Apatinib mesylate (YN968D1, Rivoceranib) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib mesylate induces both autophagy and apoptosis.
| Trivial name | YN968D1, Rivoceranib |
| Catalog Number | S2221 |
| Molecular Formula | C25H27N5O4S |
| CAS# | 1218779-75-9 |
| Inchi | InChI=1S/C24H23N5O.CH4O3S/c25-17-24(11-1-2-12-24)19-5-7-20(8-6-19)29-23(30)21-4-3-13-27-22(21)28-16-18-9-14-26-15-10-18;1-5(2,3)4/h3-10,13-15H,1-2,11-12,16H2,(H,27,28)(H,29,30);1H3,(H,2,3,4) |
| Inchi Key | FYJROXRIVQPKRY-UHFFFAOYSA-N |
| SMILES | C[S](O)(=O)=O.O=C(NC1=CC=C(C=C1)C2(CCCC2)C#N)C3=CC=CN=C3NCC4=CC=NC=C4 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Apatinib-YN968D1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Apatinib-YN968D1-chemical-structure-S2221.gif |