Apatinib
Apatinib (Rivoceranib, YN968D1) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib induces both autophagy and apoptosis.
| Trivial name | Rivoceranib, YN968D1 |
| Catalog Number | S5248 |
| Molecular Formula | C24H23N5O |
| CAS# | 811803-05-1 |
| Inchi | InChI=1S/C24H23N5O/c25-17-24(11-1-2-12-24)19-5-7-20(8-6-19)29-23(30)21-4-3-13-27-22(21)28-16-18-9-14-26-15-10-18/h3-10,13-15H,1-2,11-12,16H2,(H,27,28)(H,29,30) |
| Inchi Key | WPEWQEMJFLWMLV-UHFFFAOYSA-N |
| SMILES | O=C(NC1=CC=C(C=C1)C2(CCCC2)C#N)C3=C(NCC4=CC=NC=C4)N=CC=C3 |
| Size | 2g |
| Supplier Page | http://www.selleckchem.com/products/apatinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/apatinib-chemical-structure-s5248.gif |