Sanggenon C
Sanggenon C, a flavonoid, exerts protective effects against cardiac hypertrophy and fibrosis via suppression of the calcineurin/NFAT2 pathway. Sanggenon C inhibits mitochondrial fission to induce apoptosis by blocking the ERK signaling pathway. Sanggenon C inhibits inducible nitric oxide synthase expression in RAW264.7 cells, and TNF-α-stimulated cell adhesion and VCAM-1 expression, by suppressing NF-κB activity. Sanggenon C possesses antioxidant, anti-inflammatory and antitumor activities.
| Catalog Number | E5267 |
| Molecular Formula | C26H29NO |
| CAS# | 80651-76-9 |
| Inchi | InChI=1S/C26H29NO.C6H8O7/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,4,19-20H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b2 6-25-; |
| Inchi Key | FQZYTYWMLGAPFJ-OQKDUQJOSA-N |
| SMILES | CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3 |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/sanggenon-c.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e5267-sanggenon-c-chemical-structure-tube.png |