Simvastatin
Simvastatin is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM in cell-free assays. Simvastatin induces ferroptosis, mitophagy, autophagy and apoptosis.
| Trivial name | MK 733 |
| Catalog Number | S1792 |
| Molecular Formula | C25H38O5 |
| CAS# | 79902-63-9 |
| Inchi | InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1 |
| Inchi Key | RYMZZMVNJRMUDD-HGQWONQESA-N |
| SMILES | CCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/Simvastatin(Zocor).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Simvastatin-Zocor-chemical-structure-S1792.gif |