LCH-7749944
LCH-7749944 (GNF-PF-2356) is a novel and potent p21-activated kinase 4 (PAK4) inhibitor with an IC50 of 14.93 μM and has less potently inhibitory effect against PAK1, PAK5 and PAK6. LCH-7749944 causes successful inhibition of EGFR activity due to its inhibitory effect on PAK4.
| Trivial name | GNF-PF-2356 |
| Catalog Number | S1976 |
| Molecular Formula | C20H22N4O2 |
| CAS# | 796888-12-5 |
| SMILES | COC1=CC=CC(=C1)NC2=NC3=CC=CC=C3C(=N2)NCC4CCCO4 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/lch-7749944.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s1976-lch-7749944-chemical-structure.gif |