Apoptosis Activator 2
Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells.
Trivial name | N/A |
Catalog Number | S2927 |
Molecular Formula | C15H9Cl2NO2 |
CAS# | 79183-19-0 |
Inchi | InChI=1S/C15H9Cl2NO2/c16-11-6-5-9(7-12(11)17)8-18-13-4-2-1-3-10(13)14(19)15(18)20/h1-7H,8H2 |
Inchi Key | KGRJPLRFGLMQMV-UHFFFAOYSA-N |
SMILES | C1=CC=C2C(=C1)C(=O)C(=O)N2CC3=CC(=C(C=C3)Cl)Cl |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/apoptosis-activator-2.html |
Additional Information | https://file.selleck.cn/downloads/struct/Apoptosis-Activator-II-chemical-structure-s2927.gif |