Apoptosis Activator 2
Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells.
| Trivial name | N/A |
| Catalog Number | S2927 |
| Molecular Formula | C11H13BrFN7O4S |
| CAS# | 79183-19-0 |
| Inchi | InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23) |
| Inchi Key | FBKMWOJEPMPVTQ-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C=C1N=C(C2=NON=C2NCCNS(=O)(=O)N)NO)Br)F |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/apoptosis-activator-2.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Apoptosis-Activator-II-chemical-structure-s2927.gif |
