Masitinib
Masitinib is a novel inhibitor for Kit (c-Kit) and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms. Phase 3.
| Trivial name | AB1010 |
| Catalog Number | S1064 |
| Molecular Formula | C28H30N6OS |
| CAS# | 790299-79-5 |
| Inchi | InChI=1S/C28H30N6OS/c1-20-5-10-24(16-25(20)31-28-32-26(19-36-28)23-4-3-11-29-17-23)30-27(35)22-8-6-21(7-9-22)18-34-14-12-33(2)13-15-34/h3-11,16-17,19H,12-15,18H2,1-2H3,(H,30,35)(H,31,32) |
| Inchi Key | WJEOLQLKVOPQFV-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC(=CS4)C5=CN=CC=C5 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Masitinib-(AB1010).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Masitinib-chemical-structure-S1064.gif |