Abexinostat (PCI-24781)

Abexinostat (PCI-24781, CRA-024781) is a novel pan-HDAC inhibitor mostly targeting HDAC1 with Ki of 7 nM, modest potent to HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2.

Price Not Available 10mM/1mL Abexinostat (PCI-24781) Supplier Page

Trivial name	CRA-024781
Catalog Number	S1090
Molecular Formula	C21H23N3O5
CAS#	783355-60-2
Inchi	InChI=1S/C21H23N3O5/c1-24(2)13-17-16-5-3-4-6-18(16)29-19(17)21(26)22-11-12-28-15-9-7-14(8-10-15)20(25)23-27/h3-10,27H,11-13H2,1-2H3,(H,22,26)(H,23,25)
Inchi Key	MAUCONCHVWBMHK-UHFFFAOYSA-N
SMILES	CN(C)CC1=C(OC2=CC=CC=C21)C(=O)NCCOC3=CC=C(C=C3)C(=O)NO
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/PCI-24781.html
Additional Information	https://file.selleck.cn/downloads/struct/PCI-24781-chemical-structure-S1090.gif