Sepantronium Bromide (YM155)

Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM in HeLa-SURP-luc and CHO-SV40-luc cells; does not significantly inhibit SV40 promoter activity, but is observed to slightly inhibit the interaction of Survivin with XIAP. YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells. Phase 2.

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Catalog Number	S1130
Molecular Formula	C14H21N3O
CAS#	781661-94-7
Inchi	#N/A
Inchi Key	#N/A
SMILES	CC(N)C1CCC(CC1)C(=O)NC2=CC=NC=C2
Size	5mg
Supplier Page	http://www.selleckchem.com/products/YM155.html
Additional Information	https://file.selleck.cn/downloads/struct/YM155-chemical-structure-s1130.gif