Dinaciclib (SCH727965)

Dinaciclib (SCH727965, PS-095760) is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM in cell-free assays, respectively. It also blocks thymidine (dThd) DNA incorporation. Dinaciclib induces apoptosis through the activation of caspases 8 and 9. Phase 3.

Price Not Available 25mg Dinaciclib (SCH727965) Supplier Page

Trivial name	PS-095760
Catalog Number	S2768
Molecular Formula	C21H28N6O2
CAS#	779353-01-4
Inchi	InChI=1S/C21H28N6O2/c1-2-17-14-23-27-19(22-13-16-6-5-9-25(29)15-16)12-20(24-21(17)27)26-10-4-3-7-18(26)8-11-28/h5-6,9,12,14-15,18,22,28H,2-4,7-8,10-11,13H2,1H3/t18-/m0/s1
Inchi Key	PIMQWRZWLQKKBJ-SFHVURJKSA-N
SMILES	CCC1=C2N=C(C=C(N2N=C1)NCC3=C[N+](=CC=C3)[O-])N4CCCCC4CCO
Size	25mg
Supplier Page	http://www.selleckchem.com/products/dinaciclib-sch727965.html
Additional Information	https://file.selleck.cn/downloads/struct/Dinaciclib(SCH-727965)-chemical-structure-s2768.gif