(-)-Fenchone is a bicyclic monoterpenoid widely distributed in plants and can be extracted from Foeniculum vulgare and Peumus boldus. (-)-Fenchone has a wide range of biological activities including antioxidant, wound healing, antidiarrheal, antifungal, anti-injury sensory and bronchodilator activities. (-)-Fenchone is a potential anti-tumor compound.