Ataluren (PTC124)

Ataluren (PTC124) selectively induces ribosomal read-through of premature but not normal termination codons, with EC50 of 0.1 μM in HEK293 cells, may provide treatment for genetic disorders caused by nonsense mutations (e.g. CF caused by CFTR nonsense mutation). Phase 3.

Price Not Available 10mM/1mL Ataluren (PTC124) Supplier Page

Trivial name	N/A
Catalog Number	S6003
Molecular Formula	C15H9FN2O3
CAS#	775304-57-9
Inchi	InChI=1S/C15H9FN2O3/c16-12-7-2-1-6-11(12)14-17-13(18-21-14)9-4-3-5-10(8-9)15(19)20/h1-8H,(H,19,20)
Inchi Key	OOUGLTULBSNHNF-UHFFFAOYSA-N
SMILES	C1=CC=C(C(=C1)C2=NC(=NO2)C3=CC(=CC=C3)C(=O)O)F
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/PTC124.html
Additional Information	https://file.selleck.cn/downloads/struct/PTC124-Ataluren-chemical-structure-S6003.gif