2-Iminobiotin (hydrobromide)| ChemScene

2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5 μM for murine iNOS and rat n-cNOS, respectively. 2-Iminobiotin hydrobromide superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage[2].IC50 & Target: NO synthasesIn Vitro: Application of low concentrations of 2-Iminobiotin (2-IB; 10 ng/mL and 30 ng/mL) superimposed on hypothermia abrogates the hypoxia-induced lactate dehydrogenase (LDH) increase, resulting in LDH levels that were not different from the normoxia control.

Trivial name 2-Iminobiotin (hydrobromide)
Catalog Number CS-0115752
Alternative Name(s) Guanidinobiotin (hydrobromide)
Molecular Formula 324.24
CAS# 76985-52-9
Purity >98%
Condensed Formula C10H18BrN3O2S
Size 10mg
Supplier Page www.chemscene.com/76985-52-9.html