Leflunomide
Leflunomide is a pyrimidine synthesis and protein tyrosine kinase inhibitor belonging to the DMARD, used as an immunosuppressant agent. The active metabolite of Leflunomide is A77 1726, which inhibits dihydroorotate dehydrogenase (DHODH). Leflunomide is also an agonist of the AhR.
| Trivial name | HWA486, RS-34821, SU101 |
| Catalog Number | S1247 |
| Molecular Formula | C12H9F3N2O2 |
| CAS# | 75706-12-6 |
| Inchi | InChI=1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18) |
| Inchi Key | VHOGYURTWQBHIL-UHFFFAOYSA-N |
| SMILES | CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Leflunomide.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Leflunomide-chemical-structure-S1247.gif |